Meaheim

A young scholar named Ren makes her way to Meaheim, the last town on the border of the Dark Lands—a bizarre place where horrifying monsters run amok, and reality itself is all but unrecognizable. With the aid of a Guide named Tobia, Ren sets off on a journey into the very maw of chaos, where she must overcome monsters known as "Witches," traitorous adventures, and the godforsaken land itself to retrieve the panacea and save her brother...

(Source: Kodansha USA)