I'll Show You a Genius Omega and a Childhood Friend Beta Becoming a Fated Pair

Takayuki, a beta who works at a newspaper company, suddenly loses his job and ends up getting drunk at a bar. As he worries about what to do next, he happens to run into Shizuku, a childhood friend with whom he used to be close. Shizuku is an omega, but he works as a researcher at a center for secondary gender studies and is a genius on par with even the most elite alphas.

He’s researching a method to change one’s secondary gender artificially, and he tells Takayuki he’s looking for an assistant. Seeing it as a stroke of luck, Takayuki eagerly volunteers...but things don’t go quite as expected…

(Source: Mugenup, translated)