Saiyuyuki

A parody of the story, "Journey to the West," written in the format of 4-koma.

From MangaHelpers:

This 4-koma style manga tells the story of Gojou, an earnest disciple of the laid-back Sanzou, who is a priest of a fictional religion. The other disciples, the apathetic and violent smoker Gokou and the otaku pig Hakkai do little to help keep their band organized. It seems Gojou is the only one who takes their work seriously, and he is the one who ends up dealing with all of their secular problems. The three of them travel with their priest, as he attempts to spread his religion and avoid being eaten by demons. [tethysdust]