The Perfect Insider

On a colleague, Professor Kita's, suggestion, Associate Professor Saikawa Souhei and his student Nishinosono Moe head to Kita's research institute, where various experiments are being conducted in a low-temperature research lab. During the night a murder takes place: two graduate students are found dead in the lab. How did the killer enter the locked room? How did they leave?

Professor Saikawa and Nishinosono Moe go to camp on an island where the mysterious Professor Magata Shiki has a closed laboratory. They're curious about the murder of Magata's parents, and they manage to talk their way into the lab itself. While they are inside, a dressed-up corpse is shockingly propelled out of the door of Magata's quarters! It appears she was murdered, and she won't be the last... (Source: MangaHelpers)

Since her teenage years, Shiki Magata has been a genius programmer. After she was arrested for the murder of her parents, she was diagnosed with multiple personality disorder and acquitted of all charges. Since then, Shiki has been confined to her room at the Magata Research Institute on an isolated island in the middle of the ocean. She has never once left the room in the fifteen years since. Because Moe Nishinosono—a freshman at N University—had a personal connection with Shiki, Souhei Saikawa—Associate Professor and Moe's mentor—is about to go on a seminar trip to the campground on the island where the Magata Research Institute is located. When Saikawa visits the facility at night at Moe's invitation, they encounter a nightmare series of murders. For some reason, communication with the outside world has been cut off. Saikawa and Moe proceed with their own investigation and find a mysterious message: "Everything turns to F." It has been left on Doctor Shiki Magata's computer, where most of the data has been erased. Intuiting that these words may be the key to solving the mystery, Saikawa follows his train of thought and closes in on the truth. (Source: The BBB, edited)