A brilliant surgeon meets a tragic end during an earthquake while operating on his only sibling. Reborn into a mysterious otherworld as a deadly assassin, he must reconcile his past vocation with a new, morally fraught existence as a “revenger.” Just as he contemplates his shattered identity, a girl who mirrors his sister appears before him --–an uncanny echo that pulls him into a labyrinth of fate, duty, and supernatural suspense. (Source: Titan Manga)

In order to obtain “The End,” capable of granting any wish, determined Utaibito (musicians) must battle amongst themselves with the power of music. Is what awaits them hope, or something else? Otogi no Uta Chronicle details the backstories of each character across the different bands competing for "The End" in the series, mainly told through a CD drama. Each chapter title in the manga corresponds to a song included in the CD drama.

The story is set in a world where the Aizen Empire has conquered a world previously filled with magic and sword with the might of their guns and artillery. The story follows a group of three thieves rebelling against this established order who accidentally kidnap the princess of a fallen kingdom.