I.S. (Pronounced "Aiesu" in Japanese) is not your everyday manga, I.S. stands for "Inter Sexuality". This manga deals with very serious issues with intersexuality people. The pain they go through, the troubles they confront, and ultimately their inability to reproduce and even find a partner who will accept them as they are - It's all there in a form of manga. The series is consisted of 3 cases, each deals with different people though some cases are much longer and more dramatic than others. (Source: JanimeS, edited) *Notes: \- Includes 1 extra chapter. \- Won the Kodansha Manga Award for Shoujo in 2007.*

A man comes home one day to have his wife give him divorce papers. A woman comes home to her apartment one day to find a woman she doesn’t know wrapped in a towel coming out of the shower. They both get conned by the same real estate conman on the same house, a 4LDK. So now the man, his two sons, the woman, and her two daughters live in the same house.

A series of short stories themed around humorous non-canonical situations starring the cast of New Danganronpa V3. (Source: Danganronpa Wiki)

Ashihara Himari hates men. Or rather, she doesn't understand them. In order to alleviate this problem, her friends decide that she should confess to someone. But what if that someone unexpectedly agrees...? *Note: Chapter count includes two extra chapters.*

"I wish I had a girlfriend, I don't even care who—" "Really? Anybody? Even me?" Kaho, who has never had a boyfriend before, wanted to have a male-female relationship. Takumi, who wanted a girlfriend, just happened to be talking about it in front of her....... A heart-throbbing coming-of-age love story! (Source: Pixiv Sylph, translated)

An anthology comic of Non Non Biyori by various mangaka.

A series of 4koma comics drawn by various mangaka involving characters from the KEY visual novel Clannad.

Now, to the story of finding your true feelings... The popular game "Project Sekai Colorful Stage! feat. Hatsune Miku' First Comic Anthology! The world of 'Proseka' is expanding with this all-new comic book. Each unit's daily life is presented in a large volume!

The story starts with a 5-year-old Lynn travelling with her Japanese mother to England to meet her father. On their way there Lynn and her mother get into a tragic car accident in which Lynn’s mother dies. After getting out of the hospital Lynn moves to live in a manor owned by her father who is an English nobleman. The motherless little girl tries to adjust to high society life and get the approval of her elder step sister, Sara, whose mother has also passed away. At first Sara seems cold and distant towards her new younger sister, because she fears that Lynn’s open and cheerful personality will win over the attention of their father as well as the handsome young man who lives nearby, but... (Source: Stage Storm) *Note: Includes one-shot Moeru Bara (燃える薔薇);Bonita 1992-02-15.in vol. 12:*

A volume collection of sweet, short and fun 4 pages manga for everyone to enjoy and adore.

A spin-off of Trinity Seven: 7-nin no Mashotsukai focused on Levi Kazama.

After cleaning the Calligraphy Club room one afternoon, Kiryuu Keiki found a love letter addressed to him on the club's desk. Eager at the possibility of finally getting a girlfriend, he opens the envelope only to find the words, "I like you" along with a pair of the sender's panties. With only these panties as evidence, Keiki narrows down the identity to the four girls who helped him clean the club room that day: Tokihara Sayuki the lazy third-year president of Calligraphy Club, Koga Yuika a library committee member of foreign descent, Nanjou Mao, Keiki's slightly tsundere fellow classmate, and most awkwardly, Kiryuu Mizuha, Keiki's clean freak of a younger sister. Among at least three of these girls, Keiki believes is the one who left him the letter and their panties so with determination in his heart, he sets out to uncover which of these seemingly unorthodox ladies will become his girlfriend!