The Tokugawa shogunate uses the brainwashing "Heaven's Songs" by the top idols in Shinsengumi to subjugate the country and its people. In this Japan, writing or singing any songs besides the "Heaven's Songs" is a capital offense. Ryouma Sakamoto and the other rockers rise up and change the world with rock 'n' roll for freedom and justice.

This is a 4 page comic that is included with the Japanese and European copies of the game's manual. Though this is not included in the US release. This is a short summary to introduce the player to the main character of No More Heroes, Travis Touchdown, as well as some of the things he enjoys. It also gives a small bit of information about items, side jobs, killing jobs, Travis' motel room and exploring the town of Santa Destroy.

4-page comic that shows a short summary to re-introduce the player to the main character Travis Touchdown after a 3 year return.

Erotica Comic is a short manga and artbook by Yuusuke Kozaki released with preorders of the Hopper's Edition of No More Heroes 2: Desperate Struggle. Despite the name, it is not actually pornographic in nature. It contains four different sections. 1. **NO MORE LOSER** by Yuusuke Kozaki 2. **"Bizarre Jelly" Short Comic** (ビザールジェリー」ショートコミック) by Okama 3. **4-koma Manga** (4コママンガ) by Takayuki Mizushina